General Cell Based Assays
Eurofins Discoverx PathHunter eXpress GPR12 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0329E2ACP1M)
The PathHunter GPR12 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR12 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR12 and EA-tagged β-Arrestin-2. Activation of GPR12 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Abcam Apicidin, HDAC inhibitor, 1MG
MW 623.8 Da, Purity >95%. Potent histone deacetylase inhibitor (IC₅₀ = 0.7 nM). Inhibits cancer cell proliferation via induction of p21WAF1/Cip1 and gelsolin. Active in vitro and in vivo. Cell-permeable.
The product is subject to the following: Abcam Restricted Use Statement
Eurofins Discoverx PathHunter eXpress GPR31 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0406E2CP2L)
The PathHunter GPR31 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR31 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR31 and EA-tagged β-Arrestin-2. Activation of GPR31 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress DRD5 CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0426E2CP0L)
The PathHunter DRD5 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. dopamine) based activation of DRD5 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged DRD5 and EA-tagged β-Arrestin-2. Activation of DRD5 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Sigma Aldrich Fine Chemicals Biosciences Cell Counting Kit - 8, for quantitation of viable cell number in proliferation and cytotoxicity assays | 100 tests
Cell Counting Kit - 8, for quantitation of viable cell number in proliferation and cytotoxicity assays | 100 tests
Revvity Health Sciences Inc HTRF mAb Anti-GST Eu-Conjugate, 20,000 Assay Points
HTRF mAb Anti-GST Eu-Conjugate, 20,000 Assay Points
Revvity Health Sciences Inc HTRF Streptavidin XL665-Conjugate, 5,000 Assay Points
HTRF Streptavidin XL665-Conjugate, 5,000 Assay Points
Eurofins Discoverx PathHunter eXpress GPR146 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0365E2ACP1M)
The PathHunter GPR146 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR146 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR146 and EA-tagged β-Arrestin-2. Activation of GPR146 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR75 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0363E2ACP1M)
The PathHunter GPR75 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR75 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR75 and EA-tagged β-Arrestin-2. Activation of GPR75 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GHSR1b CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0354E2ACP1M)
The PathHunter GHSR1b eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. ghrelin) based activation of GHSR1b GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GHSR1b and EA-tagged β-Arrestin-2. Activation of GHSR1b stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR143 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0362E2ACP1M)
The PathHunter GPR143 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR143 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR143 and EA-tagged β-Arrestin-2. Activation of GPR143 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress CCRL2 CHO-K1 β-Arrestin Orphan GPCR Assay, 10-Plate Kit. (93-0333E2ACP1L)
The PathHunter CCRL2 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. CCL19) based activation of CCRL2 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged CCRL2 and EA-tagged β-Arrestin-2. Activation of CCRL2 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress PRLHR CHO-K1 β-Arrestin GPCR Assay, 10-Plate Kit. (93-0302E2CP2L)
The PathHunter PRLHR eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand (e.g. PrRP) based activation of PRLHR GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged PRLHR and EA-tagged β-Arrestin-2. Activation of PRLHR stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR20 HEK 293 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0405E1CP1M)
The PathHunter GPR20 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR20 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR20 and EA-tagged β-Arrestin-2. Activation of GPR20 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.
Eurofins Discoverx PathHunter eXpress GPR31 CHO-K1 β-Arrestin Orphan GPCR Assay, 2-Plate Kit. (93-0406E2CP2M)
The PathHunter GPR31 eXpress kit provides an easy-to-use cell based assay to study drug candidates (small molecules or biologics) targeting GPCRs. This kit assesses ligand based activation of GPR31 GPCR activity via detection of β-arrestin recruitment. The included cell line overexpresses ProLink-tagged GPR31 and EA-tagged β-Arrestin-2. Activation of GPR31 stimulates the recruitment of β-Arrestin-2 and produces EFC signal. eXpress kits are a convenient, ready-to-use format which contains all materials needed to run the assay, including single-use vials of cryopreserved cells, cell plating media, detection reagent, and assay plates. This is an orphan receptor without a known ligand. For detailed product information, User Manual and Datasheet, visit www.discoverx.com/express.